PPP2R1A Antibody - N-terminal region (ARP56741_P050)

Catalog No: ARP56741_P050

WB Suggested Anti-PPP2R1A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 293T cell lysate

Host: Mouse
Target Name: PPP2R1A
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R1A
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 85%
• Peptide Sequence: Synthetic peptide located within the following region: KAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PPP2R1A (ARP56741_P050) antibody is Catalog # AAP56741 (Previous Catalog # AAPP35422)
• Subunit: A alpha isoform
• Reference: Hong,S., (2007) J. Biol. Chem. 282 (16), 12119-12126

Target Info

• Gene Symbol: PPP2R1A
• Gene Full Name: Protein phosphatase 2, regulatory subunit A, alpha
• Alias Symbols: MRD36, PP2AA, PR65A, PP2AAALPHA, PP2A-Aalpha
• NCBI Gene Id: 5518
• Protein Name: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
• Description of Target: PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P30153
• Protein Accession #: NP_055040
• Nucleotide Accession #: NM_014225
• Protein Size (# AA): 589
• Molecular Weight: 65kDa
• Protein Interactions: CSDC2; UBC; PPP2R2A; PPP2R1B; PPP2CB; POLDIP2; MOB4; SRGAP2; ANKLE2; PSIP1; ESPL1; PPFIA3; PPFIA1; IRS4; CCDC6; TFAM; PPP1R12B; HSPA7; HSPA1A; FECH; CTNNA2; CLCN6; STRN; RPS19; RPS3; PPP2R5E; PPP2R5D; PPP2R5C; PPP2CA; PEX1; LOC730668; DGKH; RAVER1; CCDC43