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Datasheets/Manuals | Printable datasheet for anti-PPP2R1A (ARP56741_P050) antibody |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R1A |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 85% |
Peptide Sequence | Synthetic peptide located within the following region: KAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYP |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-PPP2R1A (ARP56741_P050) antibody is Catalog # AAP56741 (Previous Catalog # AAPP35422) |
Subunit | A alpha isoform |
Reference | Hong,S., (2007) J. Biol. Chem. 282 (16), 12119-12126 |
Gene Symbol | PPP2R1A |
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Gene Full Name | Protein phosphatase 2, regulatory subunit A, alpha |
Alias Symbols | MRD36, PP2AA, PR65A, PP2AAALPHA, PP2A-Aalpha |
NCBI Gene Id | 5518 |
Protein Name | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform |
Description of Target | PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Uniprot ID | P30153 |
Protein Accession # | NP_055040 |
Nucleotide Accession # | NM_014225 |
Protein Size (# AA) | 589 |
Molecular Weight | 65kDa |
Protein Interactions | CSDC2; UBC; PPP2R2A; PPP2R1B; PPP2CB; POLDIP2; MOB4; SRGAP2; ANKLE2; PSIP1; ESPL1; PPFIA3; PPFIA1; IRS4; CCDC6; TFAM; PPP1R12B; HSPA7; HSPA1A; FECH; CTNNA2; CLCN6; STRN; RPS19; RPS3; PPP2R5E; PPP2R5D; PPP2R5C; PPP2CA; PEX1; LOC730668; DGKH; RAVER1; CCDC43 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish".
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How long will it take to receive "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "PPP2R1A Antibody - N-terminal region (ARP56741_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
This target may also be called "MRD36, PP2AA, PR65A, PP2AAALPHA, PP2A-Aalpha" in publications.
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What is the shipping cost for "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "65kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PPP2R1A Antibody - N-terminal region (ARP56741_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PPP2R1A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PPP2R1A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PPP2R1A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PPP2R1A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PPP2R1A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PPP2R1A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.