PPP2CA Antibody (Phospho-Tyr307) (OASG06025)

Catalog No: OASG06025

Size:100 uL

Western Blot using SKOV3

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human PP2A-C Alpha around the phosphorylation site of Y307. Location: 250-330aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr307
• Specificity: Phospho-PP2A-C Alpha (Tyr307) Polyclonal Antibody detects endogenous levels of PP2A-C Alpha protein only when phosphorylated at Y307.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Target Info

• Gene Symbol: PPP2CA
• Gene Full Name: protein phosphatase 2, catalytic subunit, alpha isozyme
• Alias Symbols: RP-C, PP2Ac, PP2CA, NEDLBA, PP2Calpha
• NCBI Gene Id: 5515; 19052; 24672
• Description of Target: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
• Uniprot ID: P67775, P63330, P63331
• Molecular Weight: 28 kDa