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Datasheets/Manuals | Printable datasheet for anti-PPP1CC (OAAB21626) antibody |
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Predicted Species Reactivity | Human, Mouse |
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Product Format | Liquid |
Clonality | Monoclonal |
Host | Rabbit |
Application | WB |
Additional Information | Function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. |
Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Predicted Homology Based on Immunogen Sequence | Human, Mouse |
Preservative | 0.02% Sodium Azide and 50% glycerol |
Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1% BSA and 50% glycerol. |
Application Info | WB: 1:500 |
Reference | Barker H.M.,et al.Biochim. Biophys. Acta 1178:228-233(1993). Bienvenut W.V.,et al.Submitted (MAR-2009) to UniProtKB. Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB. Norman S.A.,et al.Mamm. Genome 5:41-45(1994). MacKintosh R.W.,et al.FEBS Lett. 371:236-240(1995). |
Gene Symbol | PPP1CC |
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Gene Full Name | protein phosphatase 1 catalytic subunit gamma |
Alias Symbols | PP1C, PP-1G, PPP1G |
NCBI Gene Id | 5501 |
Description of Target | The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Uniprot ID | P36873 |
Protein Accession # | NP_001231903.1 |
Nucleotide Accession # | NM_001244974.1 |
Molecular Weight | 37 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PPP1CC Antibody (OAAB21626)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
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How long will it take to receive "PPP1CC Antibody (OAAB21626)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "PPP1CC Antibody (OAAB21626)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PPP1CC Antibody (OAAB21626)"?
This target may also be called "PP1C, PP-1G, PPP1G" in publications.
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What is the shipping cost for "PPP1CC Antibody (OAAB21626)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PPP1CC Antibody (OAAB21626)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PPP1CC Antibody (OAAB21626)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "37 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PPP1CC Antibody (OAAB21626)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PPP1CC"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PPP1CC"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PPP1CC"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PPP1CC"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PPP1CC"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PPP1CC"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.