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Catalog No: ARP58652_P050-Biotin
Size:100ul
Price: $434.00
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ARP58652_P050-Biotin
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PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-PPP1CA (ARP58652_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PPP1CA
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLC
Concentration0.5 mg/ml
Blocking PeptideFor anti-PPP1CA (ARP58652_P050-Biotin) antibody is Catalog # AAP58652 (Previous Catalog # AAPP35789)
Sample Type Confirmation

PPP1CA is supported by BioGPS gene expression data to be expressed in Jurkat

ReferenceLesage,B., (2007) Biochemistry 46 (31), 8909-8919
Gene SymbolPPP1CA
Gene Full NameProtein phosphatase 1, catalytic subunit, alpha isozyme
Alias SymbolsPP1A, PP-1A, PPP1A, PP1alpha
NCBI Gene Id5499
Protein NameSerine/threonine-protein phosphatase PP1-alpha catalytic subunit
Description of TargetPPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Uniprot IDQ07161
Protein Accession #NP_001008709
Nucleotide Accession #NM_001008709
Protein Size (# AA)341
Molecular Weight38kDa
Protein InteractionsHUWE1; PPP1R2P3; CSRNP2; CSRNP1; UBC; SUMO2; SUMO3; BRCA1; Kctd20; WWOX; PKM; SCPEP1; TMOD3; MAT2B; STK24; YWHAH; XPO1; TBCB; CAPNS1; ALDH7A1; ASNS; YAP1; LMTK2; RB1; POLR2A; GSK3B; MST1R; IKBKB; CHUK; CTDP1; TNFRSF1A; tat; PPP1R15A; PPP1R13B; PLCL2; CD2B
  1. What is the species homology for "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit".

  2. How long will it take to receive "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    This target may also be called "PP1A, PP-1A, PPP1A, PP1alpha" in publications.

  5. What is the shipping cost for "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "38kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PPP1CA Antibody - N-terminal region : Biotin (ARP58652_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PPP1CA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PPP1CA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PPP1CA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PPP1CA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PPP1CA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PPP1CA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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