PPME1 Antibody (OAGA05253)

Catalog No: OAGA05253

Size:100 ul

Sample (30 ug of whole cell lysate)
A: 293T
B: A431
C: HeLa
10% SDS PAGE
diluted at 1:10000

Immunohistochemical analysis of paraffin-embedded Hela xenograft, using PPME1 antibody at 1:500 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PPME1. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:5000-1:20000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: PPME1
• Gene Full Name: protein phosphatase methylesterase 1
• Alias Symbols: PME-1, ABDH19
• NCBI Gene Id: 51400
• Protein Name: protein phosphatase methylesterase 1
• Description of Target: This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.
• Uniprot ID: Q9Y570
• Protein Accession #: NP_001258522.1
• Nucleotide Accession #: NM_001271593.1