Catalog No: OPCD01727
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OPCD01727
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Datasheets/ManualsPrintable datasheet for PPBP Recombinant Protein (OPCD01727)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ala59-Asp128
::Subcellular Location: Secreted.
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPPBP
Gene Full Namepro-platelet basic protein
Alias SymbolsBeta-TG;beta-thromboglobulin;B-TG1;chemokine (C-X-C motif) ligand 7;connective tissue-activating peptide III;CTAP3;CTAPIII;CTAP-III;CXC chemokine ligand 7;C-X-C motif chemokine 7;CXCL7;LA-PF4;LDGF;leukocyte-derived growth factor;low-affinity platelet factor IV;macrophage-derived growth factor;MDGF;NAP-2;neutrophil-activating peptide 2;PBP;platelet basic protein;SCYB7;small inducible cytokine B7;small inducible cytokine subfamily B, member 7;Small-inducible cytokine B7;TC1;TC2;TGB;TGB1;THBGB;THBGB1;thrombocidin 1;thrombocidin 2;thromboglobulin, beta-1.
NCBI Gene Id5473
Protein NamePlatelet basic protein
Description of TargetLA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
Uniprot IDP02775
Protein Accession #NP_002695.1
Nucleotide Accession #NM_002704.3
Protein Size (# AA)Ala59~Asp128
Molecular Weight14kDa
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