PPBP Antibody - FITC Conjugated (OACA01581)

Catalog No: OACA01581

Size:100ug

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: FITC
• Application: WB
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Platelet basic protein (59-125AA)
• Purification: Protein G Purified
• Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
• Reference: [1] Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library.'Wenger R.H., Wicki A.N., Walz A., Kieffer N., Clemetson K.J.Blood 73:1498-1503(1989)
  [2] Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4.'Majumdar S., Gonder D., Koutsis B., Poncz M.J. Biol. Chem. 266:5785-5789(1991)
  [3] Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus.'Zhang C., Thornton M.A., Kowalska M.A., Sachis B.S., Feldman M., Poncz M., McKenzie S.E., Reilly M.P.Blood 98:610-617(2001)
• Storage Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Target Info

• Gene Symbol: PPBP
• Gene Full Name: pro-platelet basic protein
• Alias Symbols: Beta-TG;beta-thromboglobulin;B-TG1;chemokine (C-X-C motif) ligand 7;connective tissue-activating peptide III;CTAP3;CTAPIII;CTAP-III;CXC chemokine ligand 7;C-X-C motif chemokine 7;CXCL7;LA-PF4;LDGF;leukocyte-derived growth factor;low-affinity platelet factor IV;macrophage-derived growth factor;MDGF;NAP-2;neutrophil-activating peptide 2;PBP;platelet basic protein;SCYB7;small inducible cytokine B7;small inducible cytokine subfamily B, member 7;Small-inducible cytokine B7;TC1;TC2;TGB;TGB1;THBGB;THBGB1;thrombocidin 1;thrombocidin 2;thromboglobulin, beta-1.
• NCBI Gene Id: 5473
• Protein Name: Platelet basic protein
• Description of Target: LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
• Uniprot ID: P02775
• Protein Accession #: NP_002695.1
• Nucleotide Accession #: NM_002704.3