Catalog No: OPCD06336
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OPCD06336
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Datasheets/ManualsPrintable datasheet for PPARG Recombinant Protein (OPCD06336)
Product Info
Predicted Species ReactivityBos taurus|Bovine
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationCtrl (+), SDS-PAGE, WB
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gln311-Ile500
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPPARG
Gene Full Nameperoxisome proliferator activated receptor gamma
Alias Symbolsnuclear receptor subfamily 1 group C member 3;peroxisome proliferative activated receptor, gamma;peroxisome proliferator activated receptor gamma 2;peroxisome proliferator-activated receptor gamma;PPAR-gamma.
NCBI Gene Id281993
Protein NamePeroxisome proliferator-activated receptor gamma
Description of TargetNuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels.
Uniprot IDO18971
Protein Accession #NP_851367.1
Nucleotide Accession #NM_181024.2
Protein Size (# AA)Gln311~Ile500
Molecular Weight23kDa
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