PPARG Protein (OPPA01141)

Catalog No: OPPA01141 (Formerly GWB-728440)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: PBS 50% glycerol, 0.01% azide. Physical appearance: Sterile Filtered clear solution.
• Host: E. Coli
  Product Introduction: The peroxisome proliferator activated receptors (PPARs) are ligandactivated transcription factors within the nuclear receptor superfamily, which play important roles in adipogenesis, glucose homeostasis andinflammation. Three different isotypes can be distinguished; alpha, beta and gamma. PPAR*, is mainly expressed in adipose tissue and to lesser extent in colon, the immune system and the retina. Whereas PPAR* operates in the catabolism of fatty acids in the liver, PPAR* influences the storage of fatty acids in the adipose tissue and plays a role in adipocyte differentiation. PPAR* binds to DNA as a heterodimer with retinoid X receptor (RXR), activating expression of target genes after binding ligand.
  Product Description: Peroxisome Proliferator Activated Receptor Gamma Human Recombinant is expressed in E.coli having a molecular weight of 59.2 kDa and fused to an amino terminal hexahistidine tag.
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. Avoid multiple freeze-thaw cycles.
• Purity: Greater than 95% as determined by SDS-PAGE. Mass spectrometry of tryptic digest products for identity determination.
• Peptide Sequence: MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLYZ.

Target Info

• Gene Symbol: PPARG
• Alias Symbols: GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARG5, PPARgamma
• NCBI Gene Id: 5468
• Protein Name: Peroxisome proliferator-activated receptor gamma
• Description of Target: Recombinant Human Peroxisome Proliferator Activated Receptor Gamma
• Uniprot ID: P37231
• Protein Accession #: NP_005028.4
• Protein Size (# AA): Recombinant