PPARG Antibody (Phospho-Ser112) : HRP (OABF01310-HRP)

Catalog No: OABF01310-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: WB, IHC-P, IF
• Additional Information: Subcellular location: Cytoplasm, Nucleus
  Modification: Phosphorylation (ser112)
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser112
• Purification: Purified by Protein A.
• Concentration: 0.6-0.7 mg/ml
• Application Info: WB(1:100-1000)
  IHC-P(1:100-500)
  IF(1:50-200)

Target Info

• Gene Symbol: PPARG
• Gene Full Name: peroxisome proliferator-activated receptor gamma
• Alias Symbols: GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARG5, PPARgamma
• NCBI Gene Id: 5468
• Description of Target: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
• Uniprot ID: P37231