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Catalog No: OPRB00116 (Formerly GWB-30F977)
Size:10UG
Price: $256.00
SKU
OPRB00116
Availability: Domestic: within 4-5 weeks delivery | International: 4-5 weeks
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Datasheets/ManualsPrintable datasheet for PPAR gamma Protein (OPRB00116)
Product Info
Product FormatLiquid 25mM Tris-HCl (pH 8) with 75 mM NaCl, 0.02 mM EDTA and 50% glycerol
ApplicationWB
Reconstitution and StorageStore at -20°C.
ConcentrationVaries by lot. See vial for concentration.
Purity>95% by SDS-PAGE
ReferenceSchiffrin, E.L. et al. (2003) Hypertension. 42(4): 664-68.
Description of TargetThis nuclear receptor functions as a transcription factor and plays an important role in controlling differentiation and fatty acid metabolism. Activation of this receptor appears to be vital in modulating the expression of metabolic control proteins and consequently controlling fatty acid metabolism in cardiac muscle. This marker may be a useful drug target for therapeutic intervention in cardiac disease. PPAR gamma is also involved in the pathogenesis of important metabolic disorders such as obesity and non-insulin-dependent diabetes (NIDDM). Aviva Systems Biology recombinant human PPAR gamma is expressed in E. coli with an amino-terminal hexahistidine tag.
Molecular Weight59. 2kDa
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