Catalog No: OAAF07429 (Formerly GWB-ASB208)
Size:100 ug
Price: $344.00
SKU
OAAF07429
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
ClonalityPolyclonal
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Additional InformationModification Sites: Human:Y307 Mouse:Y307 Rat:Y307
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human PP2A-alpha around the phosphorylation site of Tyr307.
PurificationThe antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Peptide SequenceSynthetic peptide located within the following region: FSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
Concentration1mg/ml
SpecificityPP2A-alpha (Phospho-Tyr307) Antibody detects endogenous levels of PP2A-alpha only when phosphorylated at Tyr307.
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application InfoWB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000
Gene SymbolPPP2CA
Gene Full Nameprotein phosphatase 2 catalytic subunit alpha
Alias SymbolsNEDLBA;PP2A-alpha;PP2Ac;PP2CA;PP2Calpha;protein phosphatase 2, catalytic subunit, alpha isozyme;replication protein C;RP-C;serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform.
NCBI Gene Id5515
Protein NameSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Description of TargetPP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Uniprot IDP67775
Molecular Weight35 kDa
  1. What is the species homology for "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    This target may also be called "NEDLBA;PP2A-alpha;PP2Ac;PP2CA;PP2Calpha;protein phosphatase 2, catalytic subunit, alpha isozyme;replication protein C;RP-C;serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform." in publications.

  5. What is the shipping cost for "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "35 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PP2A-alpha Antibody (Phospho-Tyr307) (OAAF07429)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PPP2CA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PPP2CA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PPP2CA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PPP2CA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PPP2CA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PPP2CA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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