POU2F1 Recombinant Protein (OPCD05891)

Catalog No: OPCD05891

POU2F1 Recombinant Protein (OPCD05891) using SDS-PAGE

POU2F1 Recombinant Protein (OPCD05891) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asn413-Leu671
  Subcellular Location: Nucleus
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: POU2F1
• Gene Full Name: POU class 2 homeobox 1
• Alias Symbols: NF-A1;oct-1;OCT1;oct-1B;Oct1Z;octamer-binding protein 1;octamer-binding transcription factor 1;Octamer-binding transcription factor-1;OTF1;OTF-1;POU domain, class 2, transcription factor 1.
• NCBI Gene Id: 5451
• Protein Name: POU domain, class 2, transcription factor 1
• Description of Target: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
• Uniprot ID: P14859
• Protein Accession #: NP_001185712.1
• Nucleotide Accession #: NM_001198783.1
• Protein Size (# AA): Asn413~Leu671
• Molecular Weight: 36kDa