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POLR2A Antibody (OADC00207)

Catalog#: OADC00207
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman
Product FormatLiquid. Provided in PBS containing 0.05% azide.
ApplicationCHIP, WB, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
Replacement ItemThis antibody may replace item sc-17798 from Santa Cruz Biotechnology.
PurificationProtein A purified
Concentration1 mg/mL
Datasheets/ManualsPrintable datasheet for anti-POLR2A (OADC00207) antibody
Preservative0.05% Sodium Azide
SpecificityMouse monoclonal antibody raised against RBBP4
Application InfoCHIP: 1-2 ug/CHIP
ELISA: 1:3,000
Western Blotting: 1:1,000
Immunofluorescence: 1:500
Gene SymbolPOLR2A
Official Gene Full Namepolymerase (RNA) II subunit A
Alias SymbolsRPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220
NCBI Gene Id5430;
Protein NameDNA-directed RNA polymerase II subunit RPB1
Description of TargetThis gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Swissprot IdP24928
Protein Accession #NP_000928.1
Nucleotide Accession #NM_000937.4
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express POLR2A.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express POLR2A.
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