POLR1D Antibody - middle region (ARP48787_P050)

Catalog No: ARP48787_P050

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WB Suggested Anti-POLR1D Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Cow, Dog, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POLR1D
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 93%; Human: 100%; Rabbit: 86%
• Peptide Sequence: Synthetic peptide located within the following region: TRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKDYKDQKASRNESTF
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-POLR1D (ARP48787_P050) antibody is Catalog # AAP48787 (Previous Catalog # AAPP28837)
• Subunit: RPAC2
• Reference: Andersen,J.S., (2005) Nature 433 (7021), 77-83

Target Info

• Gene Symbol: POLR1D
• Gene Full Name: Polymerase (RNA) I polypeptide D, 16kDa
• Alias Symbols: AC19, RPA9, TCS2, RPA16, RPAC2, RPC16, POLR1C, RPO1-3
• NCBI Gene Id: 51082
• Protein Name: DNA-directed RNA polymerases I and III subunit RPAC2
• Description of Target: POLR1D belongs to the archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR1D is the common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs.
• Uniprot ID: Q9Y2S0
• Protein Accession #: NP_057056
• Nucleotide Accession #: NM_015972
• Protein Size (# AA): 133
• Molecular Weight: 15kDa
• Protein Interactions: POLR1C; UBC; DNAJB4; HAX1; DNAJB6; MRPL12; PXN; NR3C1; E2F4; DDIT3; CRKL; CDC25A; POLR3H; POLR1B; POLR3B; CRCP; POLR1A; POLR3A; POLR2C; POLR3D; GRB2; NFKBIB; MAGEA11; CD3EAP;