PNPT1 Antibody (OAGA08743)

Catalog No: OAGA08743

Size:100 ul

PNPase antibody [4C11] detects PNPase protein by western blot analysis. Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PNPase antibody [4C11] diluted at a dilution of 1:1000.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Monoclonal
• Clone: 4C11
• Isotype: IgG1
• Host: Mouse
• Application: IP, WB
• Reconstitution and Storage: For short term use, store at 4C. For extended use, aliquot and store at -20C. Avoid repeated freeze-thaw cycles.
• Purification: Affinity purified by Protein G.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: PBS

Target Info

• Gene Symbol: PNPT1
• Gene Full Name: polyribonucleotide nucleotidyltransferase 1
• Alias Symbols: OLD35, DFNB70, PNPASE, old-35, COXPD13
• NCBI Gene Id: 87178
• Protein Name: polyribonucleotide nucleotidyltransferase 1, mitochondrial
• Description of Target: The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.
• Uniprot ID: Q8TCS8
• Protein Accession #: NP_149100.2
• Nucleotide Accession #: NM_033109.4