Search Antibody, Protein, and ELISA Kit Solutions

PNP Antibody - middle region : FITC (ARP75005_P050-FITC)

Click here to learn more about Aviva's By-Request Conjugation Service.
100 ul
$289.00
In Stock
Request Bulk Order Quote

Conjugation Options

ARP75005_P050 Unconjugated

ARP75005_P050-HRP Conjugated

ARP75005_P050-Biotin Conjugated

Click here to learn more about Aviva's By-Request Conjugation Service.
Gene Symbol:
PNP
Official Gene Full Name:
purine nucleoside phosphorylase
NCBI Gene Id:
4860
Protein Name:
purine nucleoside phosphorylase
Swissprot Id:
P00491
Protein Accession #:
NP_000261
Alias Symbols:
NP, PUNP, PRO1837
Description of Target:
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.
Protein Size (# AA):
289
Molecular Weight:
31kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PNP.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PNP.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human PNPH
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: IMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTW
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
0.5 mg/ml
Protein Interactions:
PNP; UBC; SUMO2; PPME1; SBDS; PSAT1; GMPS; RAB1A; PSMD5; MTAP; ENO2; HECW2; ITGA4; NADK2; TMEM177; DNAJB11; NDUFV1; GLO1; UBD; CDK2; SIRT7; UCHL5; LRIF1; CCDC90B; RBM48; ZHX1; TFB2M; NCALD; TFAM; TP53; APLP1;
Blocking Peptide:
For anti-PNP (ARP75005_P050-FITC) antibody is Catalog # AAP75005
Datasheets/Manuals:
Printable datasheet for anti-PNP (ARP75005_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm
Target Reference:
N/A

Product Reviews

Tell us what you think about this item!

Write A Review
    Please, wait...