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Catalog No: OPCD06287
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OPCD06287
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Datasheets/ManualsPrintable datasheet for PLXNA1 Recombinant Protein (OPCD06287)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Thr43-Ile300
::Subcellular Location: Cell membrane; Single-pass type I membrane protei
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPLXNA1
Gene Full Nameplexin A1
Alias SymbolsNOV;NOVP;plexin 1;plexin-A1;PLXN1;semaphorin receptor NOV.
NCBI Gene Id5361
Protein NamePlexin-A1
Description of TargetCoreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
Uniprot IDQ9UIW2
Protein Accession #NP_115618.3
Nucleotide Accession #NM_032242.3
Protein Size (# AA)Thr43~Ile300
Molecular Weight32.4kDa
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