Human PLK1 Antibody (Phospho-Thr210) (OAAQ00203)

Catalog No: OAAQ00203

Flow cytometric analysis of HeLa cells secondary antibody only negative control (blue) or untreated (red) or treated with nocodazole (green) using Phospho-PLK1 (Thr210) antibody PLK1T210-C2 at 0.01 ug/mL. Cat. #OAAQ00203.

Peptide blocking flow cytometric analysis of HeLa cells secondary antibody only negative control (light blue) or untreated (red) or treated with nocodazole (green) or untreated and blocked with phospho peptide (black) or treated and blocked with phospho peptide (gold) or untreated and blocked with non-phospho peptide (dark blue) or treated and blocked with non-phospho peptide (purple) using Phospho-PLK1 (Thr210) antibody PLK1T210-C2 at 0.01 ug/mL. Cat. #OAAQ00203.

Flow cytometric analysis of HeLa cells secondary antibody only negative control (blue) or untreated (red) or treated with nocodazole (green) using Phospho-PLK1 (Thr210) antibody PLK1T210-C2 at 0.01 ug/mL. Cat. #OAAQ00203.

Peptide blocking flow cytometric analysis of HeLa cells secondary antibody only negative control (light blue) or untreated (red) or treated with nocodazole (green) or untreated and blocked with phospho peptide (black) or treated and blocked with phospho peptide (gold) or untreated and blocked with non-phospho peptide (dark blue) or treated and blocked with non-phospho peptide (purple) using Phospho-PLK1 (Thr210) antibody PLK1T210-C2 at 0.01 ug/mL. Cat. #OAAQ00203.

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Mouse, Rat
• Product Format: Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.
• Clonality: Monoclonal
• Clone: PLK1T210-C2
• Isotype: Rabbit IgG1k
• Host: Rabbit
• Conjugation: Unconjugated
• Application: FC
• Reconstitution and Storage: -20C
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Thr210 of human phospho PLK1
• Purification: Protein A+G
• Target Post-Translational Modification: Phospho-Thr210
• Application Info: 1ug/mL - 0.001ug/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
• Reference: Petronczki M, Lenart P, and Peters J. (2008) Developmental Cell. 14:646-659.
  Seki A, Coppinger JA, Jang C, Yates III JR, and Fang G. (2008) Science. 320:1655-1658.

Target Info

• Gene Symbol: PLK1
• Gene Full Name: polo like kinase 1
• Alias Symbols: PLK, STPK13
• NCBI Gene Id: 5347
• Protein Name: serine/threonine-protein kinase PLK1
• Description of Target: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
• Uniprot ID: P53350
• Protein Accession #: NP_005021.2
• Nucleotide Accession #: NM_005030.5