Catalog No: OPCD06269
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SKU
OPCD06269
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Datasheets/ManualsPrintable datasheet for PLG Recombinant Protein (OPCD06269)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gln274-Cys560
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPLG
Gene Full Nameplasminogen
Alias SymbolsHAE4;plasmin;plasminogen.
NCBI Gene Id5340
Protein NamePlasminogen
Description of TargetPlasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
Uniprot IDP00747
Protein Accession #NP_000292.1
Nucleotide Accession #NM_000301.3
Protein Size (# AA)Gln274~Cys560
Molecular Weight38kDa
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