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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAQ00028 |
|---|
| Tested Species Reactivity | Human, Mouse |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | PLCG2Y759-G3 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | PE: Phycoerythrin |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCγ2. |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Tyr759 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | Rodriguez R, Matsuda M, Perisic O, Bravo J, Paul A, Jones NP, Light Y, Swann K, Williams RL, and Katan M. (2001) Journal of Biological Chemistry. 276:47982-47992. Zhou Q, Lee G, Brady J et al. (2012) American Journal of Human Genetics. 4:713-720 |
| Gene Symbol | PLCG2 |
|---|---|
| Gene Full Name | phospholipase C gamma 2 |
| Alias Symbols | FCAS3, APLAID, PLC-IV, PLC-gamma-2 |
| NCBI Gene Id | 5336 |
| Protein Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 |
| Description of Target | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
| Uniprot ID | P16885 |
| Protein Accession # | NP_002652.2 |
| Nucleotide Accession # | NM_002661.4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)" provided in?
This item is provided in "Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
This target may also be called "FCAS3, APLAID, PLC-IV, PLC-gamma-2" in publications.
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What is the shipping cost for "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human PLCG2 Antibody : PE (Phospho-Tyr759) (OAAQ00028)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PLCG2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PLCG2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PLCG2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PLCG2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PLCG2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PLCG2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
