Plcb2 Antibody - N-terminal region (OAAB05844)

Catalog No: OAAB05844

Size:400UL

Western blot analysis of PLCB2 Antibody (N-term) (Cat. #OAAB05844) in K562 cell line lysates (35ug/lane). PLCB2 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with PLCB2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

PLCB2 Antibody (N-term) (Cat. #OAAB05844) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Publications:

  TAS2R16 Activation Suppresses LPS-Induced Cytokine Expression in Human Gingival Fibroblasts. Front Immunol. 12, 726546 (2022). 34975834

  More...

• Predicted Species Reactivity: Human
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,IHC-P,WB
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PLCB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the N-terminal region of human PLCB2.
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Concentration: Varies by lot. See vial for concentration.
• Sample Type Confirmation:

  PLCB2 is strongly supported by BioGPS gene expression data to be expressed in K562

• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: PLCB2 Antibody (N-term) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: PLCB2
• Alias Symbols: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2.
• NCBI Gene Id: 5330
• Protein Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 1 [Homo sapiens]
• Description of Target: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
• Uniprot ID: Q00722
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_004564.2
• Molecular Weight: 134024