PKM2 Protein (OPPA01194)

Catalog No: OPPA01194 (Formerly GWB-825FA4)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: PKM2-His is supplied in 1x PBS and 50% glycerol. Physical appearance: Sterile Filtered clear solution.
• Host: E. Coli
  Product Introduction: Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.
  Product Description: PKM2 Human Recombinant is produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 62400 Dalton with an amino-terminal hexahistidine tag. The PKM2 is purified by standard chromatographic techniques.
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. Please avoid freeze thaw cycles.
• Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Target Info

• Gene Symbol: PKM2
• Alias Symbols: PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30
• NCBI Gene Id: 5315
• Protein Name: Pyruvate kinase isozymes M1/M2
• Description of Target: Recombinant Human Tumour Type M2 Pyruvate Kinase
• Uniprot ID: P14618
• Protein Accession #: NP_002645.3
• Protein Size (# AA): Recombinant