Catalog No: ARP57788_P050-Biotin
Size:100ul
Price: $434.00
SKU
ARP57788_P050-Biotin
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PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)

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Datasheets/ManualsPrintable datasheet for anti-PKM (ARP57788_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB, IHC
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PKM2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICT
Concentration0.5 mg/ml
Blocking PeptideFor anti-PKM (ARP57788_P050-Biotin) antibody is Catalog # AAP57788 (Previous Catalog # AAPP45012)
Gene SymbolPKM
Gene Full NamePyruvate kinase, muscle
Alias SymbolsPK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30
NCBI Gene Id5315
Protein NamePyruvate kinase isozymes M1/M2
Description of TargetThis gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Uniprot IDP14618
Protein Accession #NP_002645
Nucleotide Accession #NM_002654
Protein Size (# AA)531
Molecular Weight58kDa
Protein InteractionsLNX1; NXT2; HUWE1; ISG15; UBC; POLE2; FUS; SUMO2; SUMO3; STAU1; MDM2; SUZ12; EZH2; IPO11; TWF2; PDLIM5; NPLOC4; PLIN3; UBA2; EIF4A3; ANP32A; SRP14; RAD23B; PPP1CA; PIN1; CTPS1; CBS; CAPZA2; ACAT2; NLK; FBXO6; YWHAQ; RAF1; IGSF8; HDAC6; MAPK7; NPM1; CDK2;
  1. What is the species homology for "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    This target may also be called "PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30" in publications.

  5. What is the shipping cost for "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "58kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PKM2 Antibody - N-terminal region : Biotin (ARP57788_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PKM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PKM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PKM"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PKM"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PKM"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PKM"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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