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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for PKM Antibody (Phospho-Tyr105) (OABF01222) |
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| Predicted Species Reactivity | Bovine|Dog|Guinea Pig|Horse|Human|Mouse|Porcine|Rabbit|Rat |
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| Product Format | Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
| Additional Information | Target Protein: PKM2 Tyr105 |
| Reconstitution and Storage | -20°C |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human PKM2 around the phosphorylation site of Tyr105 |
| Purification | Protein A Purified |
| Concentration | 1 ug/ul |
| Application Info | WB: 1:100~1000 IHC-P: 1:100~500 Fluorescent-IHC: 1:50~200 |
| Gene Symbol | PKM |
|---|---|
| Gene Full Name | pyruvate kinase M1/2 |
| Alias Symbols | CTHBP;cytosolic thyroid hormone-binding protein;epididymis secretory protein Li 30;HEL-S-30;OIP3;OPA-interacting protein 3;p58;PK, muscle type;PK3;PKM2;pyruvate kinase 2/3;pyruvate kinase isozymes M1/M2;pyruvate kinase muscle isozyme;pyruvate kinase PKM;pyruvate kinase, muscle;TCB;THBP1;thyroid hormone-binding protein 1;thyroid hormone-binding protein, cytosolic;tumor M2-PK. |
| NCBI Gene Id | 5315 |
| Protein Name | Pyruvate kinase PKM |
| Description of Target | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. |
| Uniprot ID | P14618 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Dog|Guinea Pig|Horse|Human|Mouse|Porcine|Rabbit|Rat".
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How long will it take to receive "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
This item is available "3 to 5 business days.".
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What buffer format is "PKM Antibody (Phospho-Tyr105) (OABF01222)" provided in?
This item is provided in "Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
This target may also be called "CTHBP;cytosolic thyroid hormone-binding protein;epididymis secretory protein Li 30;HEL-S-30;OIP3;OPA-interacting protein 3;p58;PK, muscle type;PK3;PKM2;pyruvate kinase 2/3;pyruvate kinase isozymes M1/M2;pyruvate kinase muscle isozyme;pyruvate kinase PKM;pyruvate kinase, muscle;TCB;THBP1;thyroid hormone-binding protein 1;thyroid hormone-binding protein, cytosolic;tumor M2-PK." in publications.
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What is the shipping cost for "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PKM Antibody (Phospho-Tyr105) (OABF01222)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PKM"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PKM"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PKM"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PKM"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PKM"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PKM"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
