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Catalog No: OAAJ06545
Size:100 uL
Price: $319.00
SKU
OAAJ06545
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for anti-PKM (OAAJ06545) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageStore at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
ImmunogenRecombinant Proteinof human PKM2
PurificationImmunogen affinity chromatography
Concentration1 mg/mL
Gene SymbolPKM
Alias SymbolsPK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30
NCBI Gene Id5315
Protein NamePyruvate kinase PKM
Description of TargetGlycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Uniprot IDP14618
Protein Accession #NP_001193725
Nucleotide Accession #NM_001206796
Molecular Weight58 kDa
  1. What is the species homology for "PKM Antibody (OAAJ06545)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "PKM Antibody (OAAJ06545)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "PKM Antibody (OAAJ06545)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PKM Antibody (OAAJ06545)"?

    This target may also be called "PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30" in publications.

  5. What is the shipping cost for "PKM Antibody (OAAJ06545)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PKM Antibody (OAAJ06545)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PKM Antibody (OAAJ06545)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "58 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PKM Antibody (OAAJ06545)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PKM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PKM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PKM"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PKM"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PKM"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PKM"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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