PKD2 Antibody (OAGA04436)

Catalog No: OAGA04436

Size:100 ul

Sample (30 ug of whole cell lysate)
A: U87-MG
7.5% SDS PAGE
diluted at 1:500

Immunohistochemical analysis of paraffin-embedded HeLa xenograft, using Polycystin 2 antibody at 1:500 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Polycystin 2. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: PKD2
• Gene Full Name: polycystin 2, transient receptor potential cation channel
• Alias Symbols: PC2, PKD4, Pc-2, APKD2, TRPP2
• NCBI Gene Id: 5311
• Protein Name: polycystin-2
• Description of Target: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
• Uniprot ID: Q13563
• Protein Accession #: NP_000288.1
• Nucleotide Accession #: NM_000297.3