- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for PITRM1 Antibody (OACA08043) (OACA08043) |
---|
Predicted Species Reactivity | Human|Mouse |
---|---|
Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Presequence protease, mitochondrial protein (758-1037AA) |
Purification | Affinity Purified |
Preservative | 0.02% sodium azide |
Formulation | PBS with, 50% glycerol, pH7.3. |
Gene Symbol | PITRM1 |
---|---|
Gene Full Name | pitrilysin metallopeptidase 1 |
Alias Symbols | metalloprotease 1 (pitrilysin family);MP1;pitrilysin metalloproteinase 1;PreP;PreP peptidasome;presequence protease, mitochondrial;SCAR30. |
NCBI Gene Id | 10531 |
Protein Name | Presequence protease, mitochondrial |
Description of Target | Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing (PubMed:10360838, PubMed:16849325, PubMed:19196155, PubMed:24931469). Has an ATP-independent activity (PubMed:16849325). Specifically cleaves peptides in the range of 5 to 65 residues (PubMed:19196155). Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference (PubMed:10360838, PubMed:19196155, PubMed:24931469). Degrades the transit peptides of mitochondrial proteins after their cleavage (PubMed:19196155). Also degrades other unstructured peptides (PubMed:19196155). It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion (PubMed:16849325, PubMed:24931469). It is a highly efficient protease, at least toward amyloid-beta protein 40 (PubMed:24931469). Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently (PubMed:24931469). |
Uniprot ID | Q5JRX3 |
Protein Accession # | NP_001229236 |
Nucleotide Accession # | NM_001242307 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "PITRM1 Antibody (OACA08043)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
-
How long will it take to receive "PITRM1 Antibody (OACA08043)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
-
What buffer format is "PITRM1 Antibody (OACA08043)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PITRM1 Antibody (OACA08043)"?
This target may also be called "metalloprotease 1 (pitrilysin family);MP1;pitrilysin metalloproteinase 1;PreP;PreP peptidasome;presequence protease, mitochondrial;SCAR30." in publications.
-
What is the shipping cost for "PITRM1 Antibody (OACA08043)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "PITRM1 Antibody (OACA08043)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "PITRM1 Antibody (OACA08043)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PITRM1 Antibody (OACA08043)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "PITRM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "PITRM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "PITRM1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "PITRM1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "PITRM1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "PITRM1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.