PITPNM1 Antibody - FITC Conjugated (OACA00803)

Catalog No: OACA00803

Size:100ug

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: FITC
• Application: WB
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Membrane-associated phosphatidylinositol transfer protein 1 protein (1-238AA)
• Purification: Protein G Purified
• Purity: CA-AS
• Reference: [1] A mammalian homologue of the Drosophila retinal degeneration B gene: implications for the evolution of phototransduction mechanisms.'Rubboli F., Bulfone A., Bogni S., Marchitiello A., Zollo M., Borsani G., Ballabio A., Banfi S.Genes Funct. 1:205-213(1997)
  [2] Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.'Lev S., Hernandez J., Martinez R., Chen A., Plowman G., Schlessinger J.Mol. Cell. Biol. 19:2278-2288(1999)
  [3] Chromosomal localization, genomic organization and evolution of the genes encoding human phosphatidylinositol transfer protein membrane-associated (PITPNM) 1, 2 and 3.'Ocaka L., Spalluto C., Wilson D.I., Hunt D.M., Halford S.Cytogenet. Genome Res. 108:293-302(2005)
• Storage Buffer: PBS

Target Info

• Gene Symbol: PITPNM1
• Gene Full Name: phosphatidylinositol transfer protein membrane associated 1
• Alias Symbols: DRES9;drosophila retinal degeneration B homolog;membrane-associated phosphatidylinositol transfer protein 1;NIR2;NIR-2;Phosphatidylinositol transfer protein, membrane-associated 1;PITPNM;PITPnm 1;PYK2 N-terminal domain-interacting receptor 2;Rd9;RDGB;RDGB1;RDGBA;RDGBA1;retinal degeneration B alpha 1.
• NCBI Gene Id: 9600
• Protein Name: Membrane-associated phosphatidylinositol transfer protein 1
• Description of Target: Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
• Uniprot ID: O00562
• Protein Accession #: NP_001124320.1; NP_004901.2
• Nucleotide Accession #: NM_001130848.1; NM_004910.2