PIKFYVE Recombinant Protein (OPCD06184)

Catalog No: OPCD06184

PIKFYVE Recombinant Protein (OPCD06184) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Lyophilized PBS containing 0.01% SKL, 5% Trehalose
• Host: E.coli
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Thr1680-Glu1931
  Isoelectric Point: 8.6
  Subcellular Location: Membrane.
• Reconstitution and Storage: Reconstitute in 10mM PBS to a concentration of 0.1-1.0 mg/ml. Do not vortex. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Avoid repeated freeze/thaw cycles.
• Concentration: 600 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Pikfyve
• Gene Full Name: phosphoinositide kinase, FYVE type zinc finger containing
• Alias Symbols: 1-phosphatidylinositol 3-phosphate 5-kinase;5230400C17Rik;FYVE finger-containing phosphoinositide kinase;P;p235;phosphatidylinositol 3-phosphate 5-kinase type III;phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III;phosphatidylinositol-4-phosphate 5-kinase, type III;phosphoinositide kinase, FYVE finger containing;PIKfyve;Pip;Pip5k;Pip5k3;Pipk5k3;PipkIII;PIPkin-III;PtdIns(4)P-5-kinase;serine-protein kinase PIKFYVE;type III PIP kinase.
• NCBI Gene Id: 18711
• Protein Name: 1-phosphatidylinositol 3-phosphate 5-kinase
• Description of Target: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. The product of the reaction it catalyzes functions as an important regulator of vacuole homeostasis perhaps by controlling membrane flux to and/or from the vacuole.
• Uniprot ID: Q9Z1T6
• Protein Accession #: NP_001297553.1
• Nucleotide Accession #: NM_001310624.1
• Protein Size (# AA): Thr1725~Glu1976
• Molecular Weight: 33kDa