Catalog No: OPCD06184
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OPCD06184
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Datasheets/ManualsPrintable datasheet for PIKFYVE Recombinant Protein (OPCD06184)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Thr1680-Glu1931
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPikfyve
Gene Full Namephosphoinositide kinase, FYVE type zinc finger containing
Alias Symbols1-phosphatidylinositol 3-phosphate 5-kinase;5230400C17Rik;FYVE finger-containing phosphoinositide kinase;P;p235;phosphatidylinositol 3-phosphate 5-kinase type III;phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III;phosphatidylinositol-4-phosphate 5-kinase, type III;phosphoinositide kinase, FYVE finger containing;PIKfyve;Pip;Pip5k;Pip5k3;Pipk5k3;PipkIII;PIPkin-III;PtdIns(4)P-5-kinase;serine-protein kinase PIKFYVE;type III PIP kinase.
NCBI Gene Id18711
Protein Name1-phosphatidylinositol 3-phosphate 5-kinase
Description of TargetThe PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. The product of the reaction it catalyzes functions as an important regulator of vacuole homeostasis perhaps by controlling membrane flux to and/or from the vacuole.
Uniprot IDQ9Z1T6
Protein Accession #NP_001297553.1
Nucleotide Accession #NM_001310624.1
Protein Size (# AA)Thr1725~Glu1976
Molecular Weight33kDa
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