PIK3C3 Recombinant Protein (OPCD06180)

Catalog No: OPCD06180

PIK3C3 Recombinant Protein (OPCD06180) using SDS-PAGE

PIK3C3 Recombinant Protein (OPCD06180) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Isoelectric Point: 6.6
  Residues: Tyr631-Trp885
  Subcellular Location: Midbody
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: PIK3C3
• Gene Full Name: phosphatidylinositol 3-kinase catalytic subunit type 3
• Alias Symbols: hVps34;phosphatidylinositol 3-kinase catalytic subunit type 3;phosphatidylinositol 3-kinase p100 subunit;Phosphoinositide-3-kinase class 3;phosphoinositide-3-kinase, class 3;PI3K type 3;PI3-kinase type 3;PtdIns-3-kinase type 3;VPS34.
• NCBI Gene Id: 5289
• Protein Name: Phosphatidylinositol 3-kinase catalytic subunit type 3
• Description of Target: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).
• Uniprot ID: Q8NEB9
• Protein Accession #: NP_002638.2
• Nucleotide Accession #: NM_002647.3
• Protein Size (# AA): Tyr631~Trp885
• Molecular Weight: 33kDa