Catalog No: ARP63958_P050
Price: $0.00
SKU
ARP63958_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-PICALM (ARP63958_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Peptide SequenceSynthetic peptide located within the following region: DLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAW
Concentration0.5 mg/ml
Blocking PeptideFor anti-PICALM (ARP63958_P050) antibody is Catalog # AAP63958
Gene SymbolPICALM
Gene Full NamePhosphatidylinositol binding clathrin assembly protein
Alias SymbolsLAP, CALM, CLTH
NCBI Gene Id8301
Protein NamePhosphatidylinositol-binding clathrin assembly protein Ensembl ENSP00000434884
Description of TargetThis gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.
Uniprot IDE9PN05
Protein Accession #NP_001193876
Nucleotide Accession #NM_001206947
Protein Size (# AA)551
Molecular Weight60kDa
Protein InteractionsUBC; PELI2; VCAM1; ITGA4; FN1; SIRT1; ILF3; EGFR; EEF1A1; DNM2; CD55; ABCC2; ATP6V1E1; AP2A1; SH3GLB2; FLOT1; HNRNPDL; SEC24D; SEC24C; ATP6V1F; HIP1R; LAMTOR3; ITSN1; EHD2; CASP8; CLTCL1; CASP3; PLCG1; DDIT3; CLTC;
  1. What is the species homology for "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PICALM Antibody - C-terminal region (ARP63958_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    This target may also be called "LAP, CALM, CLTH" in publications.

  5. What is the shipping cost for "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PICALM Antibody - C-terminal region (ARP63958_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PICALM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PICALM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PICALM"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PICALM"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PICALM"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PICALM"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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