Catalog No: ARP45340_P050
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ARP45340_P050
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Datasheets/ManualsPrintable datasheet for anti-PI3 (ARP45340_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PI3
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%
Peptide SequenceSynthetic peptide located within the following region: RASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQV
Concentration0.5 mg/ml
Blocking PeptideFor anti-PI3 (ARP45340_P050) antibody is Catalog # AAP45340 (Previous Catalog # AAPP26316)
ReferenceWang,Z., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 724-732
Gene SymbolPI3
Gene Full NamePeptidase inhibitor 3, skin-derived
Alias SymbolsESI, WAP3, SKALP, WFDC14, cementoin
NCBI Gene Id5266
Protein NameElafin
Description of TargetPI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP19957
Protein Accession #NP_002629
Nucleotide Accession #NM_002638
Protein Size (# AA)117
Molecular Weight6kDa
Protein InteractionsEVPL; CELA1; LOR; KRT1; CSTA;
  1. What is the species homology for "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PI3 Antibody - N-terminal region (ARP45340_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    This target may also be called "ESI, WAP3, SKALP, WFDC14, cementoin" in publications.

  5. What is the shipping cost for "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "6kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PI3 Antibody - N-terminal region (ARP45340_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PI3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PI3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PI3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PI3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PI3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PI3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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