Size:400ul
$365.00
Discontinued
SKU
OASE00378
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Conjugation Options

OASE00378-FITC Conjugated

OASE00378-HRP Conjugated

OASE00378-Biotin Conjugated

Phosphoserine Antibody (OASE00378)

Catalog#: OASE00378
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This product is Genway GWB-0X0009
More Information
Predicted Species Reactivity Species Independent
Clonality Polyclonal
Host Rabbit
Application WB, IP, IHC
Additional Information Background Info: Recognizes proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine.
:: Scientific Background: Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).
:: Certificate of Analysis: 2ug/mL was sufficient for detection of phosphorylation signal in western blot analysis using human MMRU cells treated with 0.1uM okadaic acid.
Reconstitution and Storage Store at 4C. Shipping in Blue Ice or 4C.
Immunogen Phosphoserine conjugated to KLH, and phosvitin mixture
Purification Rabbit immunoglobulin
Concentration 250ug/mL
Datasheets/Manuals Printable datasheet for OASE00378
Dilution 2-4ugmL (WB), 10 ug/mg (IP), 0.5-4ug/mL (ELISA)
Target Reference 1. Goto H. et al. (2005). Nature Cell Biology 8: 180-187. 2. Blume-Jensen P. and Hunter T. (2001). Nature 411: 355-
365.
3. Downward J. (2001). Nature 411: 759-762.
4. Pawson T. and Saxton T.M. (1999). Cell 97: 675-678.
5. Ostrovsky PC. (1995). Genes Dev. 9(16): 2034-2041.
Storage Buffer PBS, 50% glycerol, 0.09% sodium azide
  1. What is the species homology for "Phosphoserine Antibody (OASE00378)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Species Independent".

  2. How long will it take to receive "Phosphoserine Antibody (OASE00378)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Phosphoserine Antibody (OASE00378)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Phosphoserine Antibody (OASE00378)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "Phosphoserine Antibody (OASE00378)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Phosphoserine Antibody (OASE00378)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Phosphoserine Antibody (OASE00378)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Phosphoserine Antibody (OASE00378)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for ""?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for ""?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with ""?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with ""?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with ""?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with ""?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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