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mBad Antibody (Phospho-Ser155) (OAAB06622)

400ul
$329.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality:
Monoclonal
Clone:
27AT937
Isotype:
IgG1
Host:
Mouse
Application:
WB
Additional Information:
Precautions: Phospho-mBad-Ser155 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
:::
Function: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 Appears to act as a link between growth factor receptor signaling and the apoptotic pathways
:::
Cellular Location: Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-111517 from Santa Cruz Biotechnology.
Immunogen:
This mouse Bad Antibody is generated from mice immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser155 of mouse Bad.
Predicted Homology Based on Immunogen Sequence:
Human; Mouse
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for OAAB06622
Application Info:
WB: 1:100~500
Gene Symbol:
Bad
Alias Symbols:
Bcl-associated death promoter
NCBI Gene Id:
12015
Protein Name:
Bcl2 antagonist of cell death
Description of Target:
Purified Phospho-specific Monoclonal Antibody (Mab)
Swissprot Id:
Q61337
Protein Accession #:
NP_031548.1
Molecular Weight:
22080 Da
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express Bad.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express Bad.

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