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Catalog No: OPCA05450
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OPCA05450
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PHOP Recombinant Protein (Escherichia coli ) (OPCA05450)

Product Info
Predicted Species ReactivityEscherichia coli
Product FormatLiquid or Lyophilized powder
Additional InformationSpecies Specificity Detail: Escherichia coli (strain K12)
Reconstitution and Storage-20°C or -80°C
FormulationTris-base, 50% glycerol
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceMRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR
Protein SequenceMRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
SourceMammalian Cells
Protein Range1-223 aa
TagN-terminal 10xHis-tagged and C-terminal Myc-tagged
ReferenceHighly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006)
Gene SymbolphoP
Gene Full NameDNA-binding transcriptional dual regulator PhoP
Alias Symbolsb1130;DNA-binding transcriptional dual regulator PhoP;ECK1116.
NCBI Gene Id945697
Protein NameTranscriptional regulatory protein PhoP
Description of TargetMember of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG (By similarity). Mediates magnesium influx to the cytosol by activation of MgtA. Promotes expression of the two-component regulatory system rstA/rstB and transcription of the hemL, mgrB, nagA, slyB, vboR and yrbL genes.
Uniprot IDP23836
Protein Accession #NP_415648
Nucleotide Accession #NC_000913
Protein Size (# AA)Recombinant
Molecular Weight29.5 kDa
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