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PHLDA2 antibody - middle region (ARP58237_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP58237_P050-FITC Conjugated

ARP58237_P050-HRP Conjugated

ARP58237_P050-Biotin Conjugated

Gene Symbol:
PHLDA2
NCBI Gene Id:
7262
Official Gene Full Name:
Pleckstrin homology-like domain, family A, member 2
Protein Name:
Pleckstrin homology-like domain family A member 2
Swissprot Id:
Q53GA4
Protein Accession #:
NP_003302
Nucleotide Accession #:
NM_003311
Alias Symbols:
BRW1C, BWR1C, HLDA2, IPL, TSSC3
Replacement Item:
This antibody may replace item sc-517086 from Santa Cruz Biotechnology.
Description of Target:
This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma
Protein Size (# AA):
152
Molecular Weight:
17kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PHLDA2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PHLDA2.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human PHLDA2
Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human: 100%
Complete computational species homology data:
Anti-PHLDA2 (ARP58237_P050)
Peptide Sequence:
Synthetic peptide located within the following region: QNRRALQDFRSRQERTAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPRT
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC;
Blocking Peptide:
For anti-PHLDA2 (ARP58237_P050) antibody is Catalog # AAP58237 (Previous Catalog # AAPP32836)
Datasheets/Manuals:
Printable datasheet for anti-PHLDA2 (ARP58237_P050) antibody
Sample Type Confirmation:

PHLDA2 is supported by BioGPS gene expression data to be expressed in HT1080

Publications:

Dai, H. et al. TSSC3 overexpression associates with growth inhibition, apoptosis induction and enhances chemotherapeutic effects in human osteosarcoma. Carcinogenesis 33, 30-40 (2012). IHC, WB, Human 22021909

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