PHF20 Antibody - N-terminal region (OAAB08402)

Catalog No: OAAB08402

Size:400ul

PHF20 Antibody (N-term) (Cat. #OAAB08402) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PHF20 antibody detected the PHF20 protein (arrow).

PHF20 Antibody (N-term) (Cat. #OAAB08402)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF20 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: PHF20 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage
  Cellular Location: Nucleus.
  Tissue Location: Expressed in heart, kidney, liver, lung, pancreas, placenta, spleen and testis. Not expressed in brain, skeletal muscle, colon, ovary, prostate, small intestine and thymus. Expressed in colon and ovary cancer cell lines while it is not expressed in the respective normal tissues
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PHF20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the N-terminal region of human PHF20.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: PHF20
• Alias Symbols: NZF, TZP, GLEA2, HCA58, TDRD20A, C20orf104
• NCBI Gene Id: 51230
• Protein Name: PHD finger protein 20
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q9BVI0
• Protein Accession #: NP_057520.2
• Molecular Weight: 115386 Da