PGP Antibody - N-terminal region (OAAB06453)

Catalog No: OAAB06453

Size:400UL

Western blot analysis of PGP Antibody (N-term) in K562 cell lysates (35ug/lane). PGP (arrow) was detected using the purified Pab.

PGP is strongly supported by BioGPS gene expression data to be expressed in K562

PGP Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PGP Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

PGP Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,IHC-P,WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human PGP.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  PGP is strongly supported by BioGPS gene expression data to be expressed in K562

• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: PGP Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: PGP
• Alias Symbols: aspartate-based ubiquitous Mg(2+)-dependent phosphatase, AUM, G3PP, glycerol-3-phosphate phosphatase, PGPase, Phosphoglycolate phosphatase.
• NCBI Gene Id: 283871
• Protein Name: Glycerol-3-phosphate phosphatase|glycerol-3-phosphate phosphatase [Homo sapiens]
• Description of Target: Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).
• Uniprot ID: A6NDG6
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001035830.1
• Molecular Weight: 34006