PEX19 Antibody - middle region (ARP81359_P050)

Catalog No: ARP81359_P050

Host: Rabbit
Target Name: PEX19
Sample Tissue: Human HepG2 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PEX19
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: KPSPAPPSTTTAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PEX19 (ARP81359_P050) antibody is Catalog # AAP81359

Target Info

• Gene Symbol: PEX19
• Gene Full Name: peroxisomal biogenesis factor 19
• Alias Symbols: PXF, HK33, PMP1, PMPI, PXMP1, PBD12A, D1S2223E
• NCBI Gene Id: 5824
• Protein Name: peroxisomal biogenesis factor 19
• Description of Target: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
• Uniprot ID: P40855
• Protein Accession #: NP_001180573.1
• Nucleotide Accession #: NM_001193644.1
• Protein Size (# AA): 299
• Molecular Weight: 33 kDa