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PDX1 Antibody - middle region (ARP87020_P050)

100 ul
$289.00
In Stock
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Gene Symbol:
PDX1
Official Gene Full Name:
pancreatic and duodenal homeobox 1
NCBI Gene Id:
3651
Protein Name:
Pancreas/duodenum homeobox protein 1
Swissprot Id:
P52945
Protein Accession #:
NP_000200.1
Nucleotide Accession #:
NM_000209.3
Alias Symbols:
GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PAGEN1
Description of Target:
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Protein Size (# AA):
283
Molecular Weight:
31 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PDX1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PDX1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human PDX1
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: KEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGG
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-PDX1 (ARP87020_P050) antibody is Catalog # AAP87020
Datasheets/Manuals:
Printable datasheet for anti-PDX1 (ARP87020_P050) antibody

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