PDGFRA Antibody - C-terminal region (ARP61086_P050)

Catalog No: ARP61086_P050

Host: Rabbit
Target Name: PGFRA
Sample Type: Thymus Tumor
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen for Anti-PDGFRA antibody is: synthetic peptide directed towards the C-terminal region of Human PGFRA
• Purification: Affinity purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%
• Peptide Sequence: Synthetic peptide located within the following region: SGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For Anti-PDGFRA antibody is Catalog # AAP61086
• Reference: N/A

Target Info

• Gene Symbol: PDGFRA
• Gene Full Name: platelet-derived growth factor receptor, alpha polypeptide
• Alias Symbols: CD140A, PDGFR2, PDGFR-2
• NCBI Gene Id: 5156
• Protein Name: Platelet-derived growth factor receptor alpha
• Description of Target: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
• Uniprot ID: P16234
• Protein Size (# AA): 1089
• Molecular Weight: 119 kDa
• Protein Interactions: CCDC155; SRPK1; FBXO25; ULBP2; UBC; TGFBR2; PIK3R1; KIT; Nedd4; GRB2; PTEN; SHF; SNX6; PDGFC; SNX4; SNX2; SLC9A3R1; STAT5B; CRKL; GRB14; STAT5A; CAV1; STAT1; SHB; ITGAV; PDGFB; PTPN11; PDGFRA; ITGB3; PDGFA; PDGFRB; PLCG1; CBL; CRK; JAK1; STAT3; CAV3;