PDGFB Recombinant Protein (OPCD06064)

Catalog No: OPCD06064

PDGFB Recombinant Protein (OPCD06064) using SDS-PAGE

PDGFB Recombinant Protein (OPCD06064) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser82-Thr190
  Subcellular Location: Secreted
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: PDGFB
• Gene Full Name: platelet derived growth factor subunit B
• Alias Symbols: becaplermin;c-sis;epididymis secretory sperm binding protein;IBGC5;PDGF subunit B;PDGF, B chain;PDGF2;PDGF-2;platelet-derived growth factor 2;platelet-derived growth factor B chain;Platelet-derived growth factor beta polypeptide;platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog);platelet-derived growth factor subunit B;platelet-derived growth factor, beta polypeptide (oncogene SIS);proto-oncogene c-Sis;SIS;SSV.
• NCBI Gene Id: 5155
• Protein Name: Platelet-derived growth factor subunit B
• Description of Target: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
• Uniprot ID: P01127
• Protein Accession #: NP_002599.1
• Nucleotide Accession #: NM_002608.3
• Protein Size (# AA): Ser82~Thr190
• Molecular Weight: 43/21kDa