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Catalog No: OPCD06063
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OPCD06063
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Datasheets/ManualsPrintable datasheet for PDGFB Recombinant Protein (OPCD06063)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Glu21-Ala241
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolPdgfb
Gene Full Nameplatelet derived growth factor, B polypeptide
Alias Symbolsc-sis;PDGF-;PDGF subunit B;PDGF-2;PDGF-B;platelet-derived growth factor B chain;platelet-derived growth factor beta polypeptide;platelet-derived growth factor subunit B;proto-oncogene c-Sis;Sis.
NCBI Gene Id18591
Protein NamePlatelet-derived growth factor subunit B
Description of TargetGrowth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
Uniprot IDP31240
Protein Accession #NP_035187.2
Nucleotide Accession #NM_011057.3
Protein Size (# AA)Glu21~Ala241
Molecular Weight55kDa
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