- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for PDCD4 Antibody (OARA02819) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid (sterile filtered) |
| Clonality | Monoclonal |
| Clone | 9G6 |
| Host | Mouse |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Additional Information | Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
| :: | Label: Unconjugated Preservative: 0.01% (w/v) Sodium Azide Stabilizer: None |
| Reconstitution and Storage | -20°C|See manual |
| Immunogen | This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Ser457 of the human Pdcd4 protein. |
| Predicted Homology Based on Immunogen Sequence | Human; Mouse; Rat |
| Concentration | 1 mg/ml |
| Application Info | ELISA: 1:20,000 - 1:100,000 WB: 1:2,000 - 1:10,000 IHC: 1:1,000 - 1:5,000 |
| Reference | Jansen AP, Camalier CE, Colburn NH (2005) Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. Cancer Res. 65(14):6034-6041.Palamarchuk A, Efanov A, Maximov V, Aqeilan RI, Croce CM, Pekarsky Y (2005) Akt phosphorylates and regulates Pdcd4 tumor suppressor protein. Cancer Res. 65 (24):11282-11286. |
| Gene Symbol | PDCD4 |
|---|---|
| Gene Full Name | programmed cell death 4 |
| Alias Symbols | H731;neoplastic transformation inhibitor protein;nuclear antigen H731;Nuclear antigen H731-like;programmed cell death 4 (neoplastic transformation inhibitor);programmed cell death protein 4;protein 197/15a. |
| NCBI Gene Id | 27250 |
| Protein Name | Programmed cell death protein 4 |
| Description of Target | Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity). |
| Uniprot ID | Q53EL6 |
| Protein Accession # | NP_055271.2; NP_663314.1 |
| Nucleotide Accession # | NM_014456.4; NM_145341.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "PDCD4 Antibody (OARA02819)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
-
How long will it take to receive "PDCD4 Antibody (OARA02819)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
-
What buffer format is "PDCD4 Antibody (OARA02819)" provided in?
This item is provided in "Liquid (sterile filtered)".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PDCD4 Antibody (OARA02819)"?
This target may also be called "H731;neoplastic transformation inhibitor protein;nuclear antigen H731;Nuclear antigen H731-like;programmed cell death 4 (neoplastic transformation inhibitor);programmed cell death protein 4;protein 197/15a." in publications.
-
What is the shipping cost for "PDCD4 Antibody (OARA02819)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "PDCD4 Antibody (OARA02819)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "PDCD4 Antibody (OARA02819)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PDCD4 Antibody (OARA02819)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "PDCD4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "PDCD4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "PDCD4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "PDCD4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "PDCD4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "PDCD4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
