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Datasheets/Manuals | Printable datasheet for PDCD1LG2 Antibody (OAPB00500) (OAPB00500) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. PD-L2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
Additional Information | Raji Cell Lysate (OCPB00175), Mouse Brain Tissue Lysate (OCPB00084) |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | PDL-2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | Anti-PD-L2 antibody (4063) was raised against a peptide corresponding to 16 amino acids near the center of human PD-L2. The immunogen is located within amino acids 140-190 of PD-L2. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse; Rat |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-PDCD1LG2 (OAPB00500) antibody is Catalog # OEPB02613 |
Application Info | PDL-2 antibody can be used for detection of PDL-2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user) |
Reference | Holling TM, Schooten E, and van Den Elsing PJ. Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. Hum. Immunol. 2004; 65:282-90.;Ishida Y, Agata Y, Shibahara K, et al. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992; 11:3887-95.;LaGier J and Pober JS. Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1). Hum. Immunol. 2006; 67:568-78.;Zhang Y, Chung Y, Bishop C, et al. Regulation of T cell activation and tolerance by PDL2. Proc. Natl. Acad. Sci. USA 2006; 103:11695-700. |
Gene Symbol | PDCD1LG2 |
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Gene Full Name | programmed cell death 1 ligand 2 |
Alias Symbols | B7 dendritic cell molecule;B7DC;B7-DC;bA574F11.2;Btdc;butyrophilin B7-DC;CD273;PD-1-ligand 2;PDCD1 ligand 2;PDCD1L2;PDL2;PD-L2;programmed cell death 1 ligand 2;programmed death ligand 2. |
NCBI Gene Id | 80380 |
Protein Name | Programmed cell death 1 ligand 2|programmed cell death 1 ligand 2 precursor [Homo sapiens] |
Description of Target | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). |
Uniprot ID | Q9BQ51 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_079515 |
Nucleotide Accession # | NM_025239.3 |
Molecular Weight | Predicted: 31kD Observed: 29 kD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PDCD1LG2 Antibody (OAPB00500)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "PDCD1LG2 Antibody (OAPB00500)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "PDCD1LG2 Antibody (OAPB00500)" provided in?
This item is provided in "Liquid. PD-L2 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PDCD1LG2 Antibody (OAPB00500)"?
This target may also be called "B7 dendritic cell molecule;B7DC;B7-DC;bA574F11.2;Btdc;butyrophilin B7-DC;CD273;PD-1-ligand 2;PDCD1 ligand 2;PDCD1L2;PDL2;PD-L2;programmed cell death 1 ligand 2;programmed death ligand 2." in publications.
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What is the shipping cost for "PDCD1LG2 Antibody (OAPB00500)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PDCD1LG2 Antibody (OAPB00500)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PDCD1LG2 Antibody (OAPB00500)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 31kD Observed: 29 kD".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PDCD1LG2 Antibody (OAPB00500)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PDCD1LG2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PDCD1LG2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PDCD1LG2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PDCD1LG2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PDCD1LG2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PDCD1LG2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.