Catalog No: OAPB00500
Size:100UG
Price: $461.00
SKU
OAPB00500
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for PDCD1LG2 Antibody (OAPB00500) (OAPB00500)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid. PD-L2 Antibody is supplied in PBS containing 0.02% sodium azide.
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Additional InformationRaji Cell Lysate (OCPB00175), Mouse Brain Tissue Lysate (OCPB00084)
::Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and StoragePDL-2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ImmunogenAnti-PD-L2 antibody (4063) was raised against a peptide corresponding to 16 amino acids near the center of human PD-L2. The immunogen is located within amino acids 140-190 of PD-L2.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman; Mouse; Rat
Concentration1 mg/ml
Blocking PeptideFor anti-PDCD1LG2 (OAPB00500) antibody is Catalog # OEPB02613
Application InfoPDL-2 antibody can be used for detection of PDL-2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
ReferenceHolling TM, Schooten E, and van Den Elsing PJ. Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. Hum. Immunol. 2004; 65:282-90.;Ishida Y, Agata Y, Shibahara K, et al. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992; 11:3887-95.;LaGier J and Pober JS. Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1). Hum. Immunol. 2006; 67:568-78.;Zhang Y, Chung Y, Bishop C, et al. Regulation of T cell activation and tolerance by PDL2. Proc. Natl. Acad. Sci. USA 2006; 103:11695-700.
Gene SymbolPDCD1LG2
Gene Full Nameprogrammed cell death 1 ligand 2
Alias SymbolsB7 dendritic cell molecule;B7DC;B7-DC;bA574F11.2;Btdc;butyrophilin B7-DC;CD273;PD-1-ligand 2;PDCD1 ligand 2;PDCD1L2;PDL2;PD-L2;programmed cell death 1 ligand 2;programmed death ligand 2.
NCBI Gene Id80380
Protein NameProgrammed cell death 1 ligand 2|programmed cell death 1 ligand 2 precursor [Homo sapiens]
Description of TargetInvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Uniprot IDQ9BQ51
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/NP_079515
Nucleotide Accession #NM_025239.3
Molecular WeightPredicted: 31kD Observed: 29 kD
  1. What is the species homology for "PDCD1LG2 Antibody (OAPB00500)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "PDCD1LG2 Antibody (OAPB00500)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "PDCD1LG2 Antibody (OAPB00500)" provided in?

    This item is provided in "Liquid. PD-L2 Antibody is supplied in PBS containing 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PDCD1LG2 Antibody (OAPB00500)"?

    This target may also be called "B7 dendritic cell molecule;B7DC;B7-DC;bA574F11.2;Btdc;butyrophilin B7-DC;CD273;PD-1-ligand 2;PDCD1 ligand 2;PDCD1L2;PDL2;PD-L2;programmed cell death 1 ligand 2;programmed death ligand 2." in publications.

  5. What is the shipping cost for "PDCD1LG2 Antibody (OAPB00500)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PDCD1LG2 Antibody (OAPB00500)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PDCD1LG2 Antibody (OAPB00500)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "Predicted: 31kD Observed: 29 kD".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PDCD1LG2 Antibody (OAPB00500)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PDCD1LG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PDCD1LG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PDCD1LG2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PDCD1LG2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PDCD1LG2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PDCD1LG2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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