PCNA Protein (OPPA01981)

Catalog No: OPPA01981 (Formerly GWB-AB332B)

Size:2ug

Product Info

• Product Format: The PCNA solution contains 50mM Tris-Acetate pH-7.5 & 1mM EDTA & 20% glycerol. Physical appearance: Sterile Filtered colorless solution.
• Host: E. Coli
  Product Introduction: PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.
  Product Description: PCNA full length Human Recombinant protein produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 62kDa which includes GST-tag fusion protein.
• Reconstitution and Storage: PCNA although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.

Target Info

• Gene Symbol: PCNA GST
• Alias Symbols: ATLD2
• NCBI Gene Id: 5111
• Protein Name: Proliferating cell nuclear antigen
• Description of Target: Recombinant Human Proliferating Cell Antigen, GST Tag
• Uniprot ID: P12004
• Protein Accession #: NP_002583.1