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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
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- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for PCNA Antibody (OABF00281) |
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Predicted Species Reactivity | Bovine|Chicken|Dog|Human|Mouse|Rabbit|Rat|Sheep |
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Product Format | Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot |
Additional Information | Subcellular location: Nucleus |
Reconstitution and Storage | -20°C |
Immunogen | KLH conjugated synthetic peptide derived from human PCNA |
Purification | Protein A Purified |
Concentration | 1 ug/ul |
Application Info | WB: 1:100 - 1000 IHC-P: : 1:100 - 500 |
Gene Symbol | PCNA |
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Gene Full Name | proliferating cell nuclear antigen |
Alias Symbols | ATLD2;cyclin;DNA polymerase delta auxiliary protein;proliferating cell nuclear antigen. |
NCBI Gene Id | 5111 |
Protein Name | Proliferating cell nuclear antigen |
Description of Target | Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways (PubMed:24939902). Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion. |
Uniprot ID | P12004 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PCNA Antibody (OABF00281)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Chicken|Dog|Human|Mouse|Rabbit|Rat|Sheep".
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How long will it take to receive "PCNA Antibody (OABF00281)"?
This item is available "3 to 5 business days.".
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What buffer format is "PCNA Antibody (OABF00281)" provided in?
This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PCNA Antibody (OABF00281)"?
This target may also be called "ATLD2;cyclin;DNA polymerase delta auxiliary protein;proliferating cell nuclear antigen." in publications.
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What is the shipping cost for "PCNA Antibody (OABF00281)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PCNA Antibody (OABF00281)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PCNA Antibody (OABF00281)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PCNA Antibody (OABF00281)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PCNA"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PCNA"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PCNA"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PCNA"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PCNA"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PCNA"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.