PCCB Antibody - middle region (OAAB05438)

Catalog No: OAAB05438 (Formerly GWB-UGECA5)

Size:400UL

Western blot analysis of PCCB Antibody (Center) in Jurkat cell lysates (35ug/lane). PCCB (arrow) was detected using the purified Pab.

PCCB is strongly supported by BioGPS gene expression data to be expressed in Jurkat

PCCB Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Bovine|Human|Mouse|Porcine
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: FC,WB
• Additional Information: Cellular Location: Mitochondrion matrix
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PCCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-107 amino acids from the Central region of human PCCB.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Human, Bovine, Mouse, Pig
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  PCCB is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Intended Use: PCCB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures
• Application Info: WB: 1:1000
  FC: 1:10~50
• Other Applications Image 1 Data: PCCB Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Reference: Yang,X., et.al.,Mol. Genet. Metab. 81 (4), 335-342 (2004)
• Gene Symbol: PCCB
• Alias Symbols: 1300012P06Rik, AI314687, PCCase beta subunit, PCCase subunit beta, propanoyl-CoA:carbon dioxide ligase beta subunit, propanoyl-CoA:carbon dioxide ligase subunit beta, propionyl CoA carboxylase, beta polypeptide, propionyl Coenzyme A carboxylase, beta polypeptide, propionyl-coA carboxylase B, propionyl-CoA carboxylase beta chain, mitochondrial, propionyl-CoA carboxylase beta subunit, R74805.
• NCBI Gene Id: 100158147|5096|515902|66904
• Protein Name: Propionyl-CoA carboxylase beta chain, mitochondrial|propionyl-CoA carboxylase beta chain, mitochondrial isoform 1 precursor [Homo sapiens]|propionyl-CoA carboxylase beta chain, mitochondrial isoform 2 precursor [Homo sapiens]
• Description of Target: PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits.
• Uniprot ID: P05166|P79384|Q2TBR0|Q99MN9
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_000523.2,NP_001171485.1
• Molecular Weight: 58216