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PAX2 Antibody - middle region (P100859_T100)

100 ul
$229.00
In Stock
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Conjugation Options

P100859_T100-FITC Conjugated

P100859_T100-HRP Conjugated

P100859_T100-Biotin Conjugated

Tested Species Reactivity:
Human
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
IHC, WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
PAX2
Official Gene Full Name:
Paired box 2
NCBI Gene Id:
5076
Protein Name:
Paired box protein Pax-2
Swissprot Id:
Q02962
Protein Accession #:
NP_003979
Nucleotide Accession #:
NM_003988
Replacement Item:
This antibody may replace item sc-130387 from Santa Cruz Biotechnology.
Description of Target:
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
Protein Size (# AA):
417
Molecular Weight:
45kDa
Purification:
Protein A purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PAX2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PAX2.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human PAX2
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Sheep: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-PAX2 (P100859_T100)
Peptide Sequence:
Synthetic peptide located within the following region: VSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDS
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
BBS7; BBS4; BBS2; BBS1; RB1; BRCA1; SFRP2; PAXIP1; WT1; MAPK8IP1; MAPK8; ID2;
Blocking Peptide:
For anti-PAX2 (P100859_T100) antibody is Catalog # AAP31220 (Previous Catalog # AAPP01965)
Datasheets/Manuals:
Printable datasheet for anti-PAX2 (P100859_T100) antibody
Target Reference:
Muratovska, A., et al., (2003) Oncogene 22 (39), 7989-7997.

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